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Bachem - 4040671.1000 - HEPCIDIN-25 (HUMAN) 1MG (Each)

  • MFR SKU: 4040671.1000
  • ITEM #: 14837425
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$1,519.34
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ITEM #: 14837425
HEPCIDIN-25 (HUMAN)^ 1mg Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal...
ITEM #: 14837425
HEPCIDIN-25 (HUMAN)^ 1mg Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. It acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity. (Disulfide bonds between Cys7 and Cys23/Cys10 and Cys13/Cys11 and Cys19/Cys14 and Cys22) CAS: 342790-21-0 C113H170N34O31S9 FW: 2789.4 . Synonym: Hepc25 (human), LEAP-1 (human), Liver-Expressed Antimicrobial Peptide (human), PLTR (human), Putative Liver Tumor Regressor (human)
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Bachem - 4040671.1000 - HEPCIDIN-25 (HUMAN) 1MG (Each)

  • Item #: 14837425
  • MFR SKU: 4040671.1000

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