Cytiva - 17519903 - MabSelect resin, 1 LItem must be purchased in units of 1

ITEM #: 12915195

Mab. Select resin is a Bio. Process protein A resin for capturing monoclonal antibodies (m. Abs) from large sample volumes.

• High-flow agarose matrix allows for high flow velocities at production scale enabling the processing of more than 10 000 L of feed in one working day.
• Oriented coupling of the ligand and optimized matrix gives high dynamic binding capacity, which reduces resin volume requirements.
• Low non-specific binding resulting in low levels of impurities in the product eluate pool
• Bio. Process resin supported for industrial applications and well-established in approved processes.
• Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.

Optimized for high capacity and throughput

The resin is based on a highly cross-linked agarose matrix with a recombinant protein A ligand. This ligand is engineered to favor an oriented coupling resulting in an affinity resin with enhanced binding capacity for IgG. The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool. Mab. Select resin is optimized for high capacity, throughput and to deliver a product pool that is high in purity and yield. High purification factor in a single step

The recombinant Protein A ligand is expressed in E. coli and is free of components of mammalian origin. The specificity of binding to the Fc region of IgG is similarto that of native protein A giving a high purification factor in a single step. In addition, the high capacity and the novel base matrix make Mab. Select resin an excellent choice for purification of m. Abs at process scale.Security and support

As a member of the Bio. Process resins range, Mab. Select resin meets industrial demands with security of supply and comprehensive technical and regulatory support.Prepacked columns and other formats

Mab. Select resin is available in the following formats: Process development scale – prepacked

• Mab. Select resin in Pre. Dictor plates – 96-well plates for high-throughput screening or process development.
• Mab. Select resin in Pre. Dictor mini columns – minitiaturized column format for high throughput process development.
• Mab. Select resin in Hi. Screen columns – optimized for method and process development.

Lab/research scale – prepacked for manual purification

Mab. Select resin in Hi. Trap columns – for easy use with a syringe, peristaltic pump, or chromatography system.Lab/research scale – prepacked for automated purification and analysis

Mab. Select resin in Hi. Trap columns – for easy use with a syringe, peristaltic pump, or chromatography system.Process scale purification – prepacked

Mab. Select resin in ReadyTo. Process NS columns – 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.
This listing is for package of 1 L.