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Cytiva - 17544010 - MacroCap SP, 25 mLItem must be purchased in units of 1

  • MFR SKU: 17544010
  • ITEM #: 12218870
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Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 12218870
MacroCap SP is a cation exchanger designed for the purification of large biomolecules such as polyethylene glycol (PEG)-modified proteins (i.e., PEGylated proteins) that are intended for use as biopharmaceuticals.
  • Strong cation exchanger for PEGylated proteins and other large biomolecules.
  • High purity and yield of PEGylated proteins at high sample loads.
  • Highly porous base matrix makes extensive surface area available for adsorption of large molecules.

MacroCap...
ITEM #: 12218870
MacroCap SP is a cation exchanger designed for the purification of large biomolecules such as polyethylene glycol (PEG)-modified proteins (i.e., PEGylated proteins) that are intended for use as biopharmaceuticals.
  • Strong cation exchanger for PEGylated proteins and other large biomolecules.
  • High purity and yield of PEGylated proteins at high sample loads.
  • Highly porous base matrix makes extensive surface area available for adsorption of large molecules.

MacroCap SP is a cation exchanger designed to separate PEGylated proteins and other large biomolecules. It allows separation of mono- from oligo- and non-PEGylated proteins with high selectivity under high load conditions. MacroCap SP is based on acrylamide-dextran copolymer resins with mass transfer properties suitable for large biomolecules. The base matrix is highly porous, which gives high available surface area for adsorption of PEGylated proteins. The large pore size also makes MacroCap SP suitable for binding other large proteins, e.g. IgM.
MacroCap SP is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, MacroCap SP meets industrial demands with security of supply and comprehensive technical and regulatory support.
This listing is for package of 25 mL.
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Cytiva - 17544010 - MacroCap SP, 25 mLItem must be purchased in units of 1

  • Item #: 12218870
  • MFR SKU: 17544010
Technical Specs
  • Chromatography technique: Ion Exchange Chromatography
  • BioProcess resin: Yes
  • Chemical stability: Commonly used aqueous buffers, 0.5 M NaOH, 0.1 M citric acid, 25% ethanol, 30% propanol, 30% methanol, 50% ethylene glycol, 1% Tween-20, and 1% SDS.
  • Flow rate: < 120 cm/h in BPG 300, 20-cm bed height or 70 cm/h in BPG 300, 30-cm bed height using process buffers with the same viscosity as water at v 3 bar (0.3 MPa)
  • Ion Exchanger Type: Strong cation exchanger
  • Ionic Capacity: 0.10-0.13 mmol H + /ml medium
  • Ligand: SO3-
  • Matrix: Acrylamide-dextran copolymer
  • Particle size, d 50V : ~50 µm
  • Storage: 4 to 30° C 0.2 M Sodium Acetate in 20% Ethanol
  • pH stability, CIP: 2– 13
  • pH stability, operational: 4– 11
  • Pack size: 25 mL
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