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Cytiva - 17549802 - MabSelect PrismA, 200 mLItem must be purchased in units of 1

  • MFR SKU: 17549802
  • ITEM #: 14184033
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ITEM #: 14184033

Mab. Select PrismA resin is available for immediate delivery.
Mab. Select PrismA affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in m. Ab purification to be met, including processing of many bispecific antibodies.
  • Enhanced dynamic binding capacity allows high mass throughput of processed m. Ab per resin volume unit.
  • Excellent alkaline...
ITEM #: 14184033

Mab. Select PrismA resin is available for immediate delivery.
Mab. Select PrismA affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in m. Ab purification to be met, including processing of many bispecific antibodies.
  • Enhanced dynamic binding capacity allows high mass throughput of processed m. Ab per resin volume unit.
  • Excellent alkaline stability enables efficient cleaning and sanitization using 0.5-1.0 M NaOH for improved process economy, bioburden control, and robustness.
  • Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
  • The PrismA protein A ligand is also available in Hi. Trap Fibro and Hi. Screen Fibro PrismA chromatography units for ultrafast purification of m. Abs.
  • Easily measure protein A leakage using the PrismA ELISA kitspecifically designed for use with Mab. Select PrismA resins.

The enhanced alkaline stability of Mab. Select PrismA also provides opportunities for more robust m. Ab purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
For samples, contact your local sales representative or customer support.
Mab. Select PrismA protein A resin builds on the proven track record of Mab. Select and Mab. Select Su. Re resins in downstream processing of monoclonal antibodies.
Learn how Bispecific antibodies (Bs. Ab) can be purified using protein A chromatography in only a single step.
This listing is for package of 200 mL.
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Cytiva - 17549802 - MabSelect PrismA, 200 mLItem must be purchased in units of 1

  • Item #: 14184033
  • MFR SKU: 17549802
Technical Specs
  • BioProcess resin: Yes
  • Ligand: Alkaline-stabilized protein A-derived (E.coli) .
  • Matrix: Highly cross-linked agarose, spherical.
  • Particle Size: 60 µm
  • Ligand Coupling Method: Epoxy
  • Dynamic binding capacity, Q B10 : 80 mg human IgG/mL resin at 6 min residence time. 65 mg human IgG/mL resin at 4 min residence time.
  • pH stability, operational: 3–12
  • pH stability, CIP: 2–14
  • Recommended maximum operational flow velocity: 300 cm/h
  • Storage: 2?C to 8?C, 20% ethanol
  • Chemical stability: Stable to commonly used aqueous buffers in protein A chromatography.
  • Certificate of Analysis: Yes
  • Chromatography technique: Antibody affinity chromatography.
  • Pack size: 200 mL
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