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Cytiva - 17549815 - HiScreen MabSelect PrismAItem must be purchased in units of 1

  • MFR SKU: 17549815
  • ITEM #: 14184028
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ITEM #: 14184028
This protein A column is prepacked with Mab. Select PrismA chromatography resin. This affinity resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand, allowing efficient cleaning between runs. This allows future demands in monoclonal antibody purification to be met, including processing of many bispecific antibodies.
  • Enhanced dynamic binding capacity compared with other protein A chromatography resins.
  • Excellent alkaline...
ITEM #: 14184028
This protein A column is prepacked with Mab. Select PrismA chromatography resin. This affinity resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand, allowing efficient cleaning between runs. This allows future demands in monoclonal antibody purification to be met, including processing of many bispecific antibodies.
  • Enhanced dynamic binding capacity compared with other protein A chromatography resins.
  • Excellent alkaline stability enables efficient cleaning and sanitization using 0.5-1.0 M NaOH.
  • Convenient method optimization and parameter screening enabled by the 10 cm bed height for efficient chromatography process development.
  • Easily measure protein A leakage using the PrismA ELISA kitspecifically designed for use with Mab. Select PrismA resins.

The enhanced alkaline stability of Mab. Select PrismA also provides opportunities for more robust m. Ab purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
Mab. Select PrismA affinity chromatography resin builds on the proven track record of Mab. Select and Mab. Select Su. Re resins in commercial monoclonal antibody and Fc-fusion protein purification.
This listing is for package of 1 × 4.7 mL.
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Cytiva - 17549815 - HiScreen MabSelect PrismAItem must be purchased in units of 1

  • Item #: 14184028
  • MFR SKU: 17549815
Technical Specs
  • Bed dimensions: 7.7 × 100 mm
  • Bed height: 100 mm
  • Bed volume: 4.7 mL
  • Column i.d.: 7.7
  • Dynamic capacity: ~ 80 mg human IgG/mL resin at 6 min residence time.
  • ~ 40 mg human IgG/mL at 2 min residence time. ( DBC at 10% breakthrough by frontal analysis at a mobile phase velocity of 100 cm/h (6 min residence time) and 150 cm/h (4 min residence time) in a lab column column at 10 cm bed height for human IgG in PBS buffer, pH 7.4. )
  • Flow velocity: < 600 cm/h ( The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography resin and the column tubing used. )
  • Pressure max. (over the packed bed during operation): 3 bar (0.3 MPa, 44 psi)
  • Chromatography technique: Antibody affinity chromatography
  • Pack size: 1 × 4.7 mL
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