Image is an illustration, may not reflect the exact product sold.


Other products by Cytiva

Cytiva - PA15401 - CypHer5E NHS EsterItem must be purchased in units of 1

  • MFR SKU: PA15401
  • ITEM #: 9631139
  • 0 Reviews / 0 Questions
$609.60
Stock Status: In Stock

ITEM #: 9631139

CypHer5E is a flexible, generic fluorophore that can be used to study most classes of cell surface receptors which internalize into the endocytic pathway when activated by a ligand.
  • Generic technology can be coupled to any receptor or epitope tag antibody.
  • Monitors any neutral to acidic event.
  • Simple fluorescence intensity increase.
  • Classic CyDye profile of two heterocycles linked by a polymethine bridge, and contains secondary nitrogen atoms in one or both...
ITEM #: 9631139

CypHer5E is a flexible, generic fluorophore that can be used to study most classes of cell surface receptors which internalize into the endocytic pathway when activated by a ligand.
  • Generic technology can be coupled to any receptor or epitope tag antibody.
  • Monitors any neutral to acidic event.
  • Simple fluorescence intensity increase.
  • Classic CyDye profile of two heterocycles linked by a polymethine bridge, and contains secondary nitrogen atoms in one or both heterocyclic rings.
  • CypHer5E has additional sulfonate groups to enhance its solubility in aqueous solutions.
  • Increased labelling efficiency and reduces adverse dye-dye interactions.

CypHer5E reports ligand-mediated receptor internalization by exploiting pH differences that occur along the endocytic pathway. CypHer5E is a red-excitable, pH-sensitive cyanine dye derivative that is minimally fluorescent at a basic pH and maximally fluorescent at an acidic pH. It is therefore well suited to report the movement of a receptor from the cell surface into acidic endosomes upon agonist stimulation.
This listing is for package of 1 mg.
Read More >>

Cytiva - PA15401 - CypHer5E NHS EsterItem must be purchased in units of 1

  • Item #: 9631139
  • MFR SKU: PA15401
  • Application: Detection of movement of a receptor from the cell surface into acidic endosomes upon agonist stimulation.
  • Absorbance: 644 nm
  • Emission Max.: 663 nm
  • Extinction Coefficient in Methanol Max.: 140000 M -1 cm -1
  • Formula Weight: 847.99
  • Protein Concentration: 250 µg
  • Solubility: Easily soluble in methanol; Very slightly soluble in cold water and hot water.
  • Physical State: Solid
  • Color: Blue
  • Reagent type: Fluorescent Labeling Reagents
  • Pack size: 1 mg

There are no questions about this product yet. Be the first to ask a question.

0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Recently Viewed Items