FD NeuroTechnologies - PK301 - FD NeuroSilver Kit II (Large), for 300 sections

ITEM #: 12957749
FD NeuroSilver Kit II is designed for the detection of degenerating neurons in fi x ed tissue sections of the central nervous system from e x perimental animals. The principle of this kit is based on the findings that some components of the neurons undergoing degeneration, such as lysosomes, a x ons, and terminals, become particularly argyrophilic. Under certain conditions, these cellular elements bind to the silver ions with high affinity. Upon reduction, the silver ions form metallic grains that are visible under a light or electron microscope.
FD NeuroSilver Kit II has been used widely in animal studies under various e x perimental conditions. This kit has proven e x tremely specific and sensitive for the detection of degenerating neuronal somata, a x ons, and terminals in both the brain and the spinal cord. It is particularly useful for the detection of small numbers of degenerating neurons that may not be demonstrable with routine histopathological techniques.
FD NeuroSilver Kit II has also been proven to be very sensitive and reliable for the detection of amyloid plaques in the brain of transgenic mice. In addition, this kit may be used for demonstrating neurodegeneration and/or amyloid plaques in tissue sections that have been processed for immunohistochemistry. The procedure of FD NeuroSilver Kit II takes appro x imately 1 hour.
FD NeuroSilver Kit II (Small) Kit Contents:

• Solution A, 250mL
• Solution B, 250mL
• Solution C, 250mL x 2
• Solution D, 250mL
• Solution E, 1mL
• Solution F, 2mL
• Solution G (5X), 500mL
• Glass Specimen Retriever (2)
• Natural Hair Paintbrush (1)
• User Manual

FD NeuroSilver Kit II (Large) Kit Contents:

• Solution A, 500mL
• Solution B, 500mL
• Solution C, 500mL x 2
• Solution D, 500mL
• Solution E, 2mL
• Solution F, 3mL
• Solution G (5X), 500mL
• Glass Specimen Retriever (2)
• Natural Hair Paintbrush (1)
• User Manual

Materials required but not included:

• Double distilled water
• Tissue culture plates (6-well)
• Histological supplies and equipment, including gelatin-coated microscope slides, glass coverslips, hair brush, staining jars, x ylene or x ylene substitutes and a light microscope

FD NeuroSilver Kit II (Large), for 300 sections
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