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Genscript - Z02756-1 - BETA-DEFENSIN 3 BD-3 HUMAN (Each)

  • MFR SKU: Z02756-1
  • ITEM #: 7012669
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ITEM #: 7012669
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The ª-defensins are distinguished from the ß-defensins by the pairing of their three disulfide bonds. To date, four human ß-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. ß-defensins are e x pressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are...
ITEM #: 7012669
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The ª-defensins are distinguished from the ß-defensins by the pairing of their three disulfide bonds. To date, four human ß-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. ß-defensins are e x pressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The ß-defensin proteins are e x pressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. ß-defensins contain a si x -cysteine motif that forms three intra-molecular disulfide bonds. ß-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues.
BD-3, Human, 1mg
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Genscript - Z02756-1 - BETA-DEFENSIN 3 BD-3 HUMAN (Each)

  • Item #: 7012669
  • MFR SKU: Z02756-1

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