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Genscript - Z03486-500 - GenCRISPR Cas13a (C2c2) Nuclease, 500ug

  • MFR SKU: Z03486-500
  • ITEM #: 23766572
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$1,099.80
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ITEM #: 23766572
GenCRISPR Cas13a (C2c2) Nuclease is an RNA-guided, RNA-targeting CRISPR enzyme, commonly referred to as C2c2. This enzyme is a member of Type VI CRISPR family containing a single protein effector with two HEPN domains. The Cas13a e x hibits two RNase activities. The first activity, a cis- sequence-specific RNA guided cleavage, activates the secondary RNase activity of the enzyme, a non-specific trans- ribonuclease activity. This Cas13a protein can be applied to detect single RNA molecules with proven...
ITEM #: 23766572
GenCRISPR Cas13a (C2c2) Nuclease is an RNA-guided, RNA-targeting CRISPR enzyme, commonly referred to as C2c2. This enzyme is a member of Type VI CRISPR family containing a single protein effector with two HEPN domains. The Cas13a e x hibits two RNase activities. The first activity, a cis- sequence-specific RNA guided cleavage, activates the secondary RNase activity of the enzyme, a non-specific trans- ribonuclease activity. This Cas13a protein can be applied to detect single RNA molecules with proven high specificity.
Recently, Cas13a has been leveraged as a diagnostic nucleic acid detection tool. Using a combination of the Cas13a cis- and trans- RNase activity and a non-target RNA tagged with a cleavage reporter ((fluorescence), the Cas13 system provides a route for reporting of the presence of a specific single RNA sequence in a sample with high specificity. The GenScript Cas13a contains a His-tag at the C-terminal.
GenCRISPR Cas13a (C2c2) Nuclease, 500ug
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Genscript - Z03486-500 - GenCRISPR Cas13a (C2c2) Nuclease, 500ug

  • Item #: 23766572
  • MFR SKU: Z03486-500

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