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Intact Genomics - 3572 - T4 UvsY Protein - 100µg

  • MFR SKU: 3572
  • ITEM #: 17841299
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$631.37
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ITEM #: 17841299
UvsY is the phage T4 recombination mediator protein, and structural and biophysical studies provide insights into its role in T4 homologous recombination. During T4 homologous recombination, the UvsX recombinase must compete with the prebound gp32 single-stranded binding protein for DNA-binding sites and T4 UvsY Protein stimulates this filament nucleation event. UvsY is a 15.8-kDa protein with properties that are consistent with its role as mediator; it stimulates the DNA-dependent ATPase activity...
ITEM #: 17841299
UvsY is the phage T4 recombination mediator protein, and structural and biophysical studies provide insights into its role in T4 homologous recombination. During T4 homologous recombination, the UvsX recombinase must compete with the prebound gp32 single-stranded binding protein for DNA-binding sites and T4 UvsY Protein stimulates this filament nucleation event. UvsY is a 15.8-kDa protein with properties that are consistent with its role as mediator; it stimulates the DNA-dependent ATPase activity of UvsX, lowers the critical concentration of UvsX that is required for activity, and promotes strand e x change. UvsY efficiently promotes the UvsX-catalyzed strand invasion reaction by recruiting to ssDNA-gp32 comple x es, promotes the release of gp32, and favors the binding of UvsX.
Product Includes
UvsY protein
10X UvsY Reaction Buffer
T4 UvsY Protein - 100µg
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Intact Genomics - 3572 - T4 UvsY Protein - 100µg

  • Item #: 17841299
  • MFR SKU: 3572

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