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Integrated BioTherapeutics - 1601-001 - Diptheria Toxin CRM197 Mutant Vaccine Carrier Protein, 1mg

  • MFR SKU: 1601-001
  • ITEM #: 12981553
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$365.38
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ITEM #: 12981553
Description: EcoCRM is CRM 197 produced as a soluble intracellular protein in E. coli. CRM 197 is genetically deto x ified diphtheria to x in. Specifically, it has a single amino acid substitution (glycine52 to glutamic acid), which causes the ADPribosyltransferase activity to be lost. CRM197 is widely used as the carrier protein for conjugate vaccines. EcoCRM is e x pressed as a recombinant protein in Escherichia coli.
Supplied by: Fina Biosolutions LLC
Size: 1 mg of protein is supplied...
ITEM #: 12981553
Description: EcoCRM is CRM 197 produced as a soluble intracellular protein in E. coli. CRM 197 is genetically deto x ified diphtheria to x in. Specifically, it has a single amino acid substitution (glycine52 to glutamic acid), which causes the ADPribosyltransferase activity to be lost. CRM197 is widely used as the carrier protein for conjugate vaccines. EcoCRM is e x pressed as a recombinant protein in Escherichia coli.
Supplied by: Fina Biosolutions LLC
Size: 1 mg of protein is supplied at a concentration of 1.0 mg/mL (by absorbance at 280 nm) in 1X PBS, pH 7.6, 10% glycerol. The theoretical molecular weight of the protein is 58.4 kDa.
Purity: >95% by HPLC
OD 260 /OD 280 = 0.57 (< 1.0, the protein is free from nucleic acid contaminant)
Endoto x in: 0.16 EU/µg
Relevance: CRM 197 is widely used as the carrier protein for conjugate vaccines. Vaccines for Haemophilus influenzae b, meningococcal disease and Streptococcus pneumoniae use CRM197. Unlike to x oids, CRM 197 has its full complement of lysines available for conjugation. It is also thought to cause less interference in multivalent vaccines. EcoCRM is stable in PBS.
Storage: -80°C, avoid repeated freeze/thaws
Intended for research use only, not for human, therapeutic, or diagnostic applications.
Diptheria Toxin CRM197 Mutant Vaccine Carrier Protein, 1mg
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Integrated BioTherapeutics - 1601-001 - Diptheria Toxin CRM197 Mutant Vaccine Carrier Protein, 1mg

  • Item #: 12981553
  • MFR SKU: 1601-001

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