Merck - 03-206 - 03-206, RIPAb+ hnRNP U - RIP Validated Antibody and Primer Set clone 3G6, from mouse

ITEM #: 11571410
RIPAb+ antibodies are evaluated using the RNA Binding Protein Immunoprecipitation (RIP) assay. Each RIPAb+ antibody set includes a negative control antibody to ensure specificity of the RIP reaction and is verified for the co-immunoprecipitation of RNA associated specifically with the immunoprecipitated RNA binding protein of interest. Where appropriate, the RIPAb+ set also includes quantitative RT-PCR control primers (RIP Primers) to biologically validate your IP results by successfully co-precipitating the specific RNA targets, such as messenger RNAs. The qPCR protocol and primer sequences are provided, allowing researchers to validate RIP protocols when using the antibody in their e x perimental conte x t. If a target specific assay is not provided, the RIPAb+ kit is validated using an automated microfluidics-based assay by enrichment of detectable RNA over control of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally diverse group of RNA binding proteins implicated in various functions. Recently, hnRNP proteins have been shown to hinder communication between factors bound to different splice sites. hnRNP-U, also termed scaffold attachment factor A (SAF-A), binds to pre-mRNA and nuclear matri x /scaffold attachment region DNA elements.
Synonyms: Scaffold attachment factor A, heterogeneous nuclear ribonucleoprotein U, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A), hnRNP U, hnRNP U protein, p120 nuclear protein
Application: This RIPAb+ hnRNP U -RIP Validated Antibody & Primer Set conveniently includes the hnRNP U antibody & the specific control PCR primers.
: UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
03-206, RIPAb+ hnRNP U - RIP Validated Antibody and Primer Set clone 3G6, from mouse
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