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Merck - 05-23-0600-25MG - Substance P - CAS 33507-63-0 - Calbiochem

  • MFR SKU: 05-23-0600-25MG
  • ITEM #: 11577070
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ITEM #: 11577070
Neuropeptide found in high concentrations in the gut.
This listing is for 25 mg Plastic ampoule

Merck - 05-23-0600-25MG - Substance P - CAS 33507-63-0 - Calbiochem

  • Item #: 11577070
  • MFR SKU: 05-23-0600-25MG
  • Overview Neuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca 2+ mobilization. Reported to activate G o α, G q/11 α, and G s α subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.
  • Catalogue Number 05-23-0600
  • Brand Family Calbiochem®
  • Synonyms RPKPQQFFGLM
  • References Roush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291.
  • Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106.
  • Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187.
  • Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192.
  • Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279.
  • Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6.
  • Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.
  • CAS number 33507-63-0
  • ATP Competitive N
  • Form White solid
  • Formulation Supplied as a trifluoroacetate salt.
  • Hill Formula CHNOS
  • Chemical formula CHNOS
  • Hygroscopic Hygroscopic
  • Reversible N
  • Sold on the basis of peptide content Y
  • Quality Level MQ100
  • Primary Target Substance P receptors
  • Purity ≥ 96% by HPLC
  • Cell permeable N
  • Peptide Content Y
  • Peptide Sequence H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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