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Merck - 05-23-3800-0.1MG - Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

  • MFR SKU: 05-23-3800-0.1MG
  • ITEM #: 11577169
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ITEM #: 11577169
Endothelin 1, Human and Porcine, CAS 117399-94-7, is a 21-amino acid polypeptide with potent vasoconstrictive action. Activates phospholipase C in fibroblasts expressing ETA receptors.
This listing is for .1 mg Plastic ampoule

Merck - 05-23-3800-0.1MG - Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

  • Item #: 11577169
  • MFR SKU: 05-23-3800-0.1MG
  • Overview A 21-amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca 2+ channels. Reported to activate phospholipase C in fibroblasts expressing ET A receptors.
  • Catalogue Number 05-23-3800
  • Brand Family Calbiochem®
  • Synonyms ET-1, CSCSSLMDKECVYFCHLDIIW
  • References Cesari, M., et al. 1996. Am. Heart J. 132, 1236.
  • Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
  • Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
  • Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
  • Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
  • Yanagisawa, M., et al. 1988. Nature 332, 411.
  • CAS number 117399-94-7
  • ATP Competitive N
  • Form White to off-white solid
  • Formulation Supplied as an acetate salt.
  • Hill Formula CHNOS
  • Chemical formula CHNOS
  • Reversible N
  • Sold on the basis of peptide content Y
  • Quality Level MQ100
  • Primary Target Potent vasoconstrictive action
  • Purity ≥ 96% by HPLC
  • Cell permeable N
  • Peptide Content Y
  • Peptide Sequence H-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Moisture Protect from moisture
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 2 weeks at -20° C.

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