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Merck - 100073-10MG - 15-PGDH Inhibitor | Calbiochem | 10 MG

  • MFR SKU: 100073-10MG
  • ITEM #: 11591209
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$275.00
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ITEM #: 11591209
The 15-PGDH Inhibitor controls the biological activity of 15-PGDH. This small molecule/inhibitor is primarily used for Membrane applications.
This listing is for 10 mg Glass bottle

Merck - 100073-10MG - 15-PGDH Inhibitor | Calbiochem | 10 MG

  • Item #: 11591209
  • MFR SKU: 100073-10MG
  • Overview A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC 50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0– 20 µ M, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.
  • Catalogue Number 100073
  • Brand Family Calbiochem®
  • Synonyms 5-(4-(2-Cyclohexylethoxy)-3-methoxybenzylidene)thiazolidine-2, 4-dione
  • References Wu, Y., et al. 2011. J. Med. Chem. 54, 5260.
  • Form Yellow solid
  • Hill Formula CHNOS
  • Chemical formula CHNOS
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 99% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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