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Merck - 1025849050 - CAFFEINE SUITABLE FOR U (50KG) (Each)

  • MFR SKU: 1025849050
  • ITEM #: 7028886
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ITEM #: 7028886
Caffeine suitable for use as excipient EMPROVE exp PH EUR, BP, USP^
This listing is for Each

Merck - 1025849050 - CAFFEINE SUITABLE FOR U (50KG) (Each)

  • Item #: 7028886
  • MFR SKU: 1025849050
  • Catalogue Number 102584
  • Synonyms 7-Methyltheobromine, 1, 3, 7-Trimethylxanthine, 3, 7-Dihydro-1, 3, 7-trimethyl-1H-purine-2, 6-dione
  • CAS number 58-08-2
  • EC index number 613-086-00-5
  • EC number 200-362-1
  • Grade Ph Eur, BP, USP
  • Hill Formula CHNO
  • Molar Mass 194.19 g/mol
  • HS Code 2939 30 00
  • Structure formula Image
  • Quality Level MQ500
  • Density 1.23 g/cm3 (18 ° C)
  • Ignition temperature >600 ° C
  • Melting Point 235 - 239 ° C
  • pH value 5.5 - 6.5 (10 g/l, HO, 20 ° C)
  • Vapor pressure 20 hPa (80 ° C)
  • Bulk density 220 kg/m3
  • Solubility 20 g/l
  • LD 50 oral LD50 Rat 367.7 mg/kg
  • Hazard Pictogram(s)
  • Hazard Statement(s) H302: Harmful if swallowed.
  • Precautionary Statement(s) P264: Wash skin thoroughly after handling.
  • P270: Do not eat, drink or smoke when using this product.
  • P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
  • P501: Dispose of contents/ container to an approved waste disposal plant.
  • Signal Word Warning
  • Storage class 10 - 13 Other liquids and solids
  • WGK WGK 1 slightly hazardous to water
  • Disposal 3
  • Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
  • Categories of danger harmful
  • Storage Store at +2° C to +30° C.
  • Declaration (railroad and road) ADR, RID Kein Gefahrgut
  • Declaration (transport by air) IATA-DGR No Dangerous Good
  • Declaration (transport by sea) IMDG-Code No Dangerous Good
  • Assay (perchloric acid titration, calculated on dried substance) 98.5 - 101.5 %
  • Assay (HPLC, calc. on anhydrous substance) 98.5 - 101.0 %
  • Identity (IR) passes test
  • Identity (HPLC) passes test
  • Identity (wet chemistry) passes test
  • Identity (Melting point) 234 - 239 ° C
  • Appearance of solution (1%; water) passes test
  • Acidity passes test
  • Sulfate (SO) ≤ 500 ppm
  • Chloroform (HS-GC) ≤ 60 ppm
  • Related substances (HPLC, EP) (Highest single impurity) ≤ 0.10 %
  • Related substances (HPLC, EP) (Sum of all impurities) ≤ 0.10 %
  • Chromatographic purity (USP) (Highest single impurity) ≤ 0.1 %
  • Chromatographic purity (USP) (Sum of all impurities) ≤ 0.1 %
  • Theophylline (HPLC) ≤ 0.10 %
  • Other residual solvents (ICH Q3C) excluded by the manufacturing process
  • Sulfated ash ≤ 0.1 %
  • Loss on Drying (105 ° C) ≤ 0.5 %
  • Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
  • Corresponds to Ph Eur, BP, USP

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