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Merck - 104550-25MG - ACA - CAS 110683-10-8 - Calbiochem

  • MFR SKU: 104550-25MG
  • ITEM #: 5256380
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ITEM #: 5256380
ACA^ ( [N-(p-Amylcinnamoyl)anthranilic acid]). White solid. Inhibits epinephrine-stimulated thromboxane production via inhibition of phospholipase A2 (PLA2) in human platelets. Also blocks glucose-induced insulin secretion by pancreatic b-cells. Exhibits moderate leukotriene antagonist activity.
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Merck - 104550-25MG - ACA - CAS 110683-10-8 - Calbiochem

  • Item #: 5256380
  • MFR SKU: 104550-25MG
  • Overview A cell-permeable inhibitor of phospholipase A 2 that blocks epinephrine-stimulated thromboxane production in platelets. Inhibits ATP-stimulated phosphatidylcholine (PC) secretion in alveolar type II cells. Also blocks phorbol ester and A23187-induced PC secretion in type II cells. Reported to block glucose-induced insulin secretion by pancreatic β-cells. Exhibits moderate leukotriene antagonist activity.
  • Catalogue Number 104550
  • Brand Family Calbiochem®
  • Synonyms N-( p -Amylcinnamoyl)anthranilic Acid
  • References Liu, L., et al. 1999. J. Cell. Biochem. 72, 103.
  • Simonsson, E., et al. 1998. Diabetes 47, 1436.
  • Konrad, R.J., et al. 1992. Biochim. Biophys. Acta 1135, 215.
  • Banga, H.S., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 9197.
  • CAS number 110683-10-8
  • ATP Competitive N
  • Form White solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target A2PLA2
  • Purity ≥ 99% by HPLC
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +15° C to +30° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.

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