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Merck - 1064451000 - SODIUM L-GLUTAMATE MONOHYDRATE (Each)

  • MFR SKU: 1064451000
  • ITEM #: 6309857
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ITEM #: 6309857
Sodium l-glutamate monohydrate suitable for use as excipient EMPROVE* exp FCC, NF, e 621^
This listing is for Each

Merck - 1064451000 - SODIUM L-GLUTAMATE MONOHYDRATE (Each)

  • Item #: 6309857
  • MFR SKU: 1064451000
  • Catalogue Number 106445
  • Synonyms Sodium L-glutamate Monohydrate
  • CAS number 6106-04-3
  • EC number 205-538-1
  • Grade ChP, FCC, NF, E 621
  • Hill Formula CHNNaO * HO
  • Molar Mass 187.13 g/mol
  • HS Code 2922 42 00
  • Structure formula Image
  • Quality Level MQ500
  • Melting Point >200 ° C (sublimed)
  • pH value 6.7 - 7.2 (50 g/l, HO, 20 ° C)
  • Bulk density 680 kg/m3
  • Solubility 600 g/l
  • LD 50 oral LD50 Rat 15800 mg/kg
  • Storage class 10 - 13 Other liquids and solids
  • WGK WGK 2 obviously hazardous to water
  • Disposal 3
  • Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
  • Storage Store at +2° C to +30° C.
  • Declaration (railroad and road) ADR, RID Kein Gefahrgut
  • Declaration (transport by air) IATA-DGR No Dangerous Good
  • Declaration (transport by sea) IMDG-Code No Dangerous Good
  • Assay (perchloric acid titration, calculated on dried substance) 99.0 - 100.5 %
  • Identity (IR-spectrum) passes test
  • Identity (wet chemistry) passes test
  • Identity (TLC) passes test
  • Appearance white to almost white, crystalline powder or fine crystals
  • Appearance of solution (100g/l, water) colorless and not more intense in turbidity than control solution according to NF and FCC
  • Transmittance of solution (100 g/l, water) ≥ 98.0 %
  • Spec. rotation (α 20/D, 100g/l, hydrochloric acid 2mol/l, calc. on dried substance) +24.8 to +25.3
  • pH (50g/l CO-free water) 6.7 - 7.2
  • Alkalinity or acidity (100 g/l, water) 6.7 - 7.2
  • Chloride (Cl) ≤ 500 ppm
  • Sulfate (SO) ≤ 300 ppm
  • NH (Ammonium) ≤ 200 ppm
  • Fe (Iron) ≤ 10 ppm
  • Heavy metals (as Pb) ≤ 10 ppm
  • Al (Aluminium) ≤ 5 ppm
  • As (Arsenic) ≤ 1 ppm
  • Mn (Manganese) ≤ 15 ppm
  • Pb (Lead) ≤ 1 ppm
  • Cu (Copper) ≤ 10 ppm
  • Zn (Zinc) ≤ 10 ppm
  • Other amino acids (TLC) ≤ 0.5 %
  • 5-Oxopyrrolidine-2-carboxylic acid (Pyroglutamic acid) ≤ 0.2 %
  • Residual solvents (ICH Q3C) excluded by manufacturing process
  • Loss on drying (100° C, 5h) ≤ 0.1 %
  • Bacterial endotoxins ≤ 25 I.U./g
  • Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
  • Corresponds to ChP, NF, FCC, E621
  • Conforms to the purity criteria on food additives according to the current European Commission Regulation.

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