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Merck - 118415-60UG - ADP-HPD, Dihydrate, Ammonium Salt | Calbiochem | 60UG

  • MFR SKU: 118415-60UG
  • ITEM #: 7010263
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ITEM #: 7010263
ADP-HPD, Dihydrate, Ammonium Salt, is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
This listing is for 60 μg Plastic ampoule

Merck - 118415-60UG - ADP-HPD, Dihydrate, Ammonium Salt | Calbiochem | 60UG

  • Item #: 7010263
  • MFR SKU: 118415-60UG
  • Overview An amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC 50 = 120 nM). Does not affect the activities of either poly(ADP-ribose) polymerase (PARP) or NAD:arginine mono(ADP-ribosyl)-transferase A even at 1 mM concentration. Also acts as an inhibitor of NAD glycohydrolase from Bungarus fasciatus venom at much higher concentrations (IC 50 = 260 µ M). Note: 1 set = 5 x 60 µg.
  • Note: 1 set = 5 x 60 µg
  • Catalogue Number 118415
  • Brand Family Calbiochem®
  • Synonyms Adenosine 5-diphosphate (Hydroxymethyl)pyrrolidinediol, NH
  • References Vispe, S., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 9886.
  • Slama, J.T., et al. 1995. J. Med. Chem. 38, 389.
  • Slama, J.T., et al. 1995. J. Med. Chem. 38, 4332.
  • ATP Competitive N
  • Form White lyophilized solid
  • Hill Formula CHNOP · NH · 2HO
  • Chemical formula CHNOP · NH · 2HO
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Application ADP-HPD, Dihydrate, Ammonium Salt, is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
  • Primary Target PARG 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 120 nM against poly(ADP-ribose) glycohydrolase (PARG)
  • Purity ≥ 95% by HPLC
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze at -20° C. Stock solutions are stable for up to 1 week at -20° C.
  • Packaged under inert gas Packaged under inert gas

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