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Merck - 119113-5MG - Luciferase Inhibitor I | CAS 352341-26-5 | Calbiochem | 5 MG

  • MFR SKU: 119113-5MG
  • ITEM #: 11572918
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ITEM #: 11572918
The Luciferase Inhibitor I, also referenced under CAS 352341-26-5, controls the biological activity of Luciferase.
This listing is for 5 mg Glass bottle

Merck - 119113-5MG - Luciferase Inhibitor I | CAS 352341-26-5 | Calbiochem | 5 MG

  • Item #: 11572918
  • MFR SKU: 119113-5MG
  • Overview A 3, 5-diaryl-oxadiazole compound that acts as an inhibitor against the ATP-dependent Photuris pennsylvanica ( lucPpe ) and Photinus pyralis ( lucPpy ) luciferase activity (IC 50 = 0.08 and 2.8 µ M, respectively, with 10 µ M ATP, 10 µ M luciferin, and 10 nM respective enzyme) and effectively inhibits lucPpe -based commercial luciferase-luciferin formulations (IC 50 = 5, 13.5, and 12.7 µ M against Promega's Kinase-Glo ® , Kinase-Glo ® Plus, and Kinase-Glo ® Max, respectively, at a 3-fold formulation dilution and 6.77 µ M ATP). Unlike Luciferase Inhibitor II (Cat. No. 119114 ), Luciferase Inhibitor I is noncompetitive with respect to either luciferin or ATP.
  • Catalogue Number 119113
  • Brand Family Calbiochem®
  • Synonyms 2-(5-(2-Methoxyphenyl)-1, 2, 4-oxadiazol-3-yl)pyridine
  • References Auld, D.S., et al. 2009. J. Med. Chem. 52, 1450.
  • Auld, D.S., et al. 2008. J. Med. Chem. 51, 2372.
  • CAS number 352341-26-5
  • Declaration Marketed by Promega Corp. under the registered trademarks.
  • Form Off-white solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 95% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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