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Merck - 119114-5MG - Luciferase Inhibitor II | CAS 10205-56-8 | Calbiochem | 5 MG

  • MFR SKU: 119114-5MG
  • ITEM #: 11572919
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$234.50
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ITEM #: 11572919
The Luciferase Inhibitor II, also referenced under CAS 10205-56-8, controls the biological activity of Luciferase.
This listing is for 5 mg Glass bottle

Merck - 119114-5MG - Luciferase Inhibitor II | CAS 10205-56-8 | Calbiochem | 5 MG

  • Item #: 11572919
  • MFR SKU: 119114-5MG
  • Overview A 2-arylbenzothiazole compound that acts as an inhibitor against the ATP-dependent Photinus pyralis ( lucPpy ) and Photuris pennsylvanica ( lucPpe ) luciferase activity (IC 50 = 0.2 and 0.32 µ M, respectively, with 10 µ M ATP, 10 µ M luciferin, and 10 nM respective enzyme). Unlike Luciferase Inhibitor I (Cat. No. 119113 ), Luciferase Inhibitor II is competitive with respect to luciferin and exhibits reduced potency against lucPpe -based commercial luciferase-luciferin formulations with high luciferin concentration (IC 50 = 10 µ M against Promega's Kinase-Glo ® ; ineffective against Kinase-Glo ® Plus and Kinase-Glo ® Max; at a 3-fold formulation dilution and 6.77 µ M ATP).
  • Catalogue Number 119114
  • Brand Family Calbiochem®
  • Synonyms 4-(1, 3-Benzothiazol-2-yl)-N, N-dimethylaniline
  • References Auld, D.S., et al. 2009. J. Med. Chem. 52, 1450.
  • Auld, D.S., et al. 2008. J. Med. Chem. 51, 2372.
  • CAS number 10205-56-8
  • Declaration Marketed by Promega Corp. under the registered trademarks.
  • Form Pale green solid
  • Hill Formula CHNS
  • Chemical formula CHNS
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 95% by HPLC
  • R Phrase R: 22
  • Harmful if swallowed.
  • S Phrase S: 22-26-36
  • Do not breathe dust.
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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