Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - 172104-50MG - Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem

  • MFR SKU: 172104-50MG
  • ITEM #: 11574585
  • 0 Reviews / 0 Questions
$127.95
Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 11574585
The Anaphase-Promoting Complex Inhibitor, TAME, also referenced under CAS 1784-03-8, controls the biological activity of Anaphase-Promoting Complex. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
This listing is for 50 mg Glass bottle

Merck - 172104-50MG - Anaphase-Promoting Complex Inhibitor, TAME - CAS 1784-03-8 - Calbiochem

  • Item #: 11574585
  • MFR SKU: 172104-50MG
  • Overview TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1. It stabilizes APC substrates and is shown to inhibit cyclin proteolysis in mitotic Xenopus egg extract with an IC 50 = 12 µ M.
  • Catalogue Number 172104
  • Brand Family Calbiochem®
  • Synonyms TAME hydrochloride, APC/C Inhibitor I, APC/C-Cdc20 Interaction Inhibitor I, Cyclosome Inhibitor I
  • References Sackton, K.L., et al. 2014. Nature. In press.
  • Zeng, X., et al. 2010. Cancer Cell 18, 382.
  • CAS number 1784-03-8
  • Form White solid
  • Hill Formula CHNOS · HCl
  • Chemical formula CHNOS · HCl
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 98% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

There are no questions about this product yet. Be the first to ask a question.

0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Recently Viewed Items