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Merck - 189490-100MG - Autophagy Inhibitor, 3-MA | CAS 5142-23-4 | Calbiochem | 100 MG

  • MFR SKU: 189490-100MG
  • ITEM #: 11574629
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ITEM #: 11574629
Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis following serum/potassium deprivation.
This listing is for 100 mg Glass bottle

Merck - 189490-100MG - Autophagy Inhibitor, 3-MA | CAS 5142-23-4 | Calbiochem | 100 MG

  • Item #: 11574629
  • MFR SKU: 189490-100MG
  • Overview A widely used cell-permeable autophagic sequestration blocker that effectly protects cerebellar granule cells from apoptosis following serum/potassium deprivation. Although a known class III PI3K inhibitor (IC 50 = 4.5 mM in cell-free enzymatic assays), 3-MA exhibits quite distinct pharmacological properties from those of two other PI3K inhibitors, LY 294002 (Cat. Nos. 440202 and 440204 ) and Wortmannin (Cat. No. 681675 )
  • Catalogue Number 189490
  • Brand Family Calbiochem®
  • Synonyms 3-Methyladenine
  • References Canu, N., et al. 2005. J. Neurochem. 92, 1228.
  • Hirosako, K., et al. 2004. Biochem. Biophys. Res. Commun. 316, 845.
  • Beugnet, A., et al. 2003. Biochem. J. 372, 555.
  • Eskelinen, E.L., et al. 2002. Traffic 3, 878.
  • Petiot, A., et al. 2000. J. Biol. Chem. 275, 992.
  • Seglen, P.O. and Gordon, P.B., 1982. Proc. Natl. Acad. Sci. USA 79, 1889.
  • CAS number 5142-23-4
  • Form White to faint yellow powder
  • Hill Formula CHN
  • Chemical formula CHN
  • Structure formula Image
  • Quality Level MQ100
  • Application Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis following serum/potassium deprivation.
  • Purity ≥ 95% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C. Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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