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Merck - 196418-1GM - BAPTA, Tetrasodium Salt | CAS 126824-24-6 | Calbiochem | 1GM

  • MFR SKU: 196418-1GM
  • ITEM #: 7009907
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ITEM #: 7009907
BAPTA, Tetrasodium^ ( [1, 2-bis(o-Aminophenoxy)ethane-N, N, N'' , N'' -tetraacetic acid, sodium]). Off-white solid. PROTECT FROM LIGHT. Ca2+ chelator exhibiting a 105-fold greater affinity for Ca2+ (110 nM) than for Mg2+.
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Merck - 196418-1GM - BAPTA, Tetrasodium Salt | CAS 126824-24-6 | Calbiochem | 1GM

  • Item #: 7009907
  • MFR SKU: 196418-1GM
  • Overview Ca 2+ chelator exhibiting a 10 5 -fold greater affinity for Ca 2+ (K d = 110 nM) than for Mg 2+ . After BAPTA complexes with Ca 2+ , the UV spectrum shifts from 254 to 279 nm at pH >6.0. Useful for spectrophotometric monitoring of extracellular Ca 2+ levels, especially transient phenomena, because of its insensitivity to pH. Useful for the measurement and control of Ca 2+ levels in eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg 2+ . Has neuroprotective effects in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy.
  • Catalogue Number 196418
  • Brand Family Calbiochem®
  • Synonyms 1, 2- bis ( o -Aminophenoxy)ethane-N, N, N, N-tetraacetic Acid, 4Na
  • References DeLorenzo, R.J., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14482.
  • Li, L., et al. 1995. J. Cell Physiol. 163, 105.
  • Tymianski, M., et al. 1994. J. Neurophysiol. 72, 1973.
  • CAS number 126824-24-6
  • Form White to off-white solid
  • Hill Formula CHNO · 4Na
  • Chemical formula CHNO · 4Na
  • Hygroscopic Hygroscopic
  • Structure formula Image
  • Quality Level MQ100
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage -20° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot, purge with inert gas and freeze (-20° C). To increase stability in solution, store at a high pH (>10). Stock solutions are stable for up to 1 month at -20° C.

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