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Merck - 1.06447.9029 - TRI-SODIUM CITRATE DIHYDRATE 25 (Each)

  • MFR SKU: 1.06447.9029
  • ITEM #: 9537027
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ITEM #: 9537027
tri-Sodium citrate dihydrate^ tri-Sodium citrate dihydrate, Suitable for use as excipient EMPROVE* exp Ph Eur, BP, JP, USP, E 332, Cas No. 6132-04-3, Molecular Formula: C6H5Na3O7*2 H2O, Synonyms: Trisodium Citrate, Sodium Citrate, Dihydrate, Size: 25kg
This listing is for Each

Merck - 1.06447.9029 - TRI-SODIUM CITRATE DIHYDRATE 25 (Each)

  • Item #: 9537027
  • MFR SKU: 1.06447.9029
Technical Specs
  • Catalogue Number 106447
  • Synonyms Trisodium Citrate, Sodium Citrate, Dihydrate
  • CAS number 6132-04-3
  • EC number 200-675-3
  • Grade Ph Eur, BP, ChP, JP, USP, ACS, E 331
  • Hill Formula CHNaO * 2 HO
  • Molar Mass 294.10 g/mol
  • HS Code 2918 15 00
  • Structure formula Image
  • Quality Level MQ500
  • Melting Point 300 ° C (anhydrous substance)
  • pH value 7.5 - 9.0 (50 g/l, HO, 25 ° C)
  • Bulk density 600 kg/m3
  • Solubility 720 g/l
  • LD 50 oral LD50 Rat > 8000 mg/kg
  • Storage class 10 - 13 Other liquids and solids
  • WGK WGK 1 slightly hazardous to water
  • Disposal 3
  • Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
  • Storage Store at +2° C to +30° C.
  • Declaration (railroad and road) ADR, RID Kein Gefahrgut
  • Declaration (transport by air) IATA-DGR No Dangerous Good
  • Declaration (transport by sea) IMDG-Code No Dangerous Good
  • Assay (perchloric acid titration, calculated on dried substance) 99.0 - 100.5 %
  • Assay (perchloric acid titration) ≥ 99.0 %
  • Identity passes test
  • Appearance of solution passes test
  • Acidity or alkalinity passes test
  • Alkalinity passes test
  • pH-value (5%; water) 7.5 - 8.5
  • pH-value (5%; water; 25° C) 7.0 - 9.0
  • Insoluble matter ≤ 0.005 %
  • Chloride (Cl) ≤ 0.003 %
  • Sulfate (SO) ≤ 0.005 %
  • Heavy metals (as Pb) ≤ 0.0005 %
  • Heavy metals (ACS) ≤ 0.0005 %
  • As (Arsenic) ≤ 0.0001 %
  • Ba (Barium) ≤ 0.003 %
  • Ca (Calcium) ≤ 0.005 %
  • Fe (Iron) ≤ 0.0005 %
  • Hg (Mercury) ≤ 0.0001 %
  • NH (Ammonia) ≤ 0.003 %
  • Pb (Lead) ≤ 0.0001 %
  • Calcium salts or oxalate ≤ 0.005 %
  • Oxalate (CO) ≤ 0.01 %
  • Tartrate (as CHO) passes test
  • Residual solvents (ICH Q3C) excluded by manufacturing process
  • Readily carbonisable substance passes test
  • Loss on drying (180° C) 11.0 - 13.0 %
  • Water 11.0 - 13.0 %
  • Total aerobic microbial count ≤ 100 CFU/g
  • Total yeast and mould count ≤ 10 CFU/g
  • Salmonella species (absent in 10 g) passes test
  • E.coli (absent in 1 g) passes test
  • Staphylococcus aureus (absent in 1 g) passes test
  • Pseudomonas aeruginosa (absent in 1 g) passes test
  • Bile tolerante gram negative bacteria (absent in 1g) passes test
  • Candida albicans (absent in 1 g) passes test
  • Endotoxins ≤ 2.5 I.U./g
  • DNases (Exo- and endonucleases) (not detectable) passes test
  • RNases (not detectable) passes test
  • Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
  • Corresponds to Ph Eur, BP, ChP, JP, USP, ACS, E 331
  • Conforms to the purity criteria on food additives according to the current European Commission Regulation.
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