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Merck - 203732-100UG - Brevetoxin PbTx-2, Ptychodiscus brevis (Brevetoxin B) | CAS 79580-28-2 | Calbiochem | 100UG

  • MFR SKU: 203732-100UG
  • ITEM #: 3441658
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ITEM #: 3441658
Brevetoxin PbTx-2, Ptychodiscus brevis^ (Brevetoxin B; GbTx-2). Light tan solid. PACKAGED UNDER INERT GAS. Purity: >95% by HPLC. Soluble in EtOAc, MeOH and H2O. RTECS XW5886000, CAS 79580-28-2, M.W. 895.1. WARNING! Toxic. LD50 of

Merck - 203732-100UG - Brevetoxin PbTx-2, Ptychodiscus brevis (Brevetoxin B) | CAS 79580-28-2 | Calbiochem | 100UG

  • Item #: 3441658
  • MFR SKU: 203732-100UG
  • Overview Lipid-soluble polyether neurotoxin that binds to Na + channels on nerves and muscles causing an excessive influx of Na + across membranes. Binds at site 5 on the voltage-sensitive Na + channel.
  • Catalogue Number 203732
  • Brand Family Calbiochem®
  • Synonyms Brevetoxin B, GbTx-2
  • References Edwards, R.A., et al. 1992. Mol. Brain Res. 14, 64.
  • Trainer, V.L. 1991. Mol. Pharmacol. 40, 988.
  • Tsai, M.C., and Chen, M.L. 1991. Br. J. Pharmacol. 103, 1126.
  • Trainer, V.L., et al. 1990. ACS Symposium Series 418, 166.
  • Baden, G. 1989. FASEB J. 3, 1807.
  • Baden, D.G., et al. 1988. Toxicon 26, 97.
  • Poli, M.A., et al. 1986. Mol. Pharmacol. 30, 129.
  • Shimizu, Y., et al. 1986. J. Am. Chem. Soc. 108, 514.
  • Nakanishi, K. 1985. Toxicon 23, 473.
  • Baden, D.G., et al. 1982. Toxicon 19, 455.
  • Catterfall, W.A., and Risk, M. 1981. Mol. Pharmacol. 19, 345.
  • CAS number 79580-28-2
  • ATP Competitive N
  • Form Tan to white solid
  • Hill Formula CHO
  • Chemical formula CHO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Neurotoxin that binds to Na+ channels on nerves and muscles.
  • Purity ≥ 95% by HPLC
  • Cell permeable N
  • RTECS XW5886000
  • R Phrase R: 26/27/28
  • Very toxic by inhalation, in contact with skin and if swallowed.
  • S Phrase S: 22-36/37/39-45
  • Do not breathe dust.
  • Wear suitable protective clothing, gloves and eye/face protection.
  • In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
  • Ship Code Blue Ice Only
  • Toxicity Highly Toxic
  • Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
  • Storage -20° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot, purge with iniert gas and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • From Catalog: Solubitlity- removed acetone, EtOAc
  • End use certificate Y
  • Packaged under inert gas Packaged under inert gas

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