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Merck - 205546-500MG - Caffeic Acid | CAS 331-39-5 | Calbiochem | 500MG

  • MFR SKU: 205546-500MG
  • ITEM #: 3441783
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ITEM #: 3441783
Caffeic Acid^ (3, 4-Dihydroxycinnamic acid). Natural dietary compound with reported anti-carcinogenic and anti-inflammatory properties. Selective, non-competitive 5-lipoxygenase inhibitor. Purity: >=98% by TLC. Soluble in DMSO and ethanol. CAS: 331-39-5. FW: 180.2. Yellow crystalline solid, 500mg.
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Merck - 205546-500MG - Caffeic Acid | CAS 331-39-5 | Calbiochem | 500MG

  • Item #: 3441783
  • MFR SKU: 205546-500MG
  • Overview A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID 50 = 3.7 µ M). Inhibits Cu 2+ -induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
  • Catalogue Number 205546
  • Brand Family Calbiochem®
  • Synonyms 3, 4-Dihydroxycinnamic Acid
  • References Yamanaka, N., et al. 1997. FEBS Lett. 405, 186.
  • Chan, W.S., et al. 1995. Anticancer Res. 15, 703.
  • Ploemen, J.H., et al. 1993. Food Chem. Toxicol. 31, 475.
  • Koshihara, Y., et al. 1984. Biochim. Biophys. Acta 792, 92.
  • CAS number 331-39-5
  • ATP Competitive N
  • Form Tan crystalline solid
  • Hill Formula CHO
  • Chemical formula CHO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target 5-lipoxygenase 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 3.7 µ M against 5-lipoxygenase
  • Purity ≥ 95% by HPLC
  • Cell permeable Y
  • RTECS GD8950000
  • R Phrase R: 40
  • Limited evidence of a carcinogenic effect.
  • S Phrase S: 36/37
  • Wear suitable protective clothing and gloves.
  • Ship Code Ambient Temperature Only
  • Toxicity Carcinogenic / Teratogenic
  • Storage +2° C to +8° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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