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Merck - 218765-5MG - Caspase-9 Substrate I, Fluorogenic (Ac-LEHD-AFC) | Calbiochem | 5MG

  • MFR SKU: 218765-5MG
  • ITEM #: 3032541
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ITEM #: 3032541
Caspase-9 Substrate I, Fluorogenic, Calbiochem^ (Ac-LEHD-AFC; Ac-Leu-Glu-His-Asp-AFC). A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). May also act as a substrate for caspase-4 and caspase-5. Purity: >=95% by HPLC. Soluble in DMSO. FW: 765.7. White solid, 5mg.
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Merck - 218765-5MG - Caspase-9 Substrate I, Fluorogenic (Ac-LEHD-AFC) | Calbiochem | 5MG

  • Item #: 3032541
  • MFR SKU: 218765-5MG
  • Overview A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). May also act as a substrate for caspase-4 and caspase-5. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
  • Catalogue Number 218765
  • Brand Family Calbiochem®
  • Synonyms Ac-LEHD-AFC
  • References Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
  • Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
  • Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
  • ATP Competitive N
  • Form White solid
  • Formulation Supplied as a trifluoroacetate salt.
  • Hill Formula CHFNO
  • Chemical formula CHFNO
  • Reversible N
  • Quality Level MQ100
  • Primary Target A fluorogenic substrate for caspase-9
  • Purity ≥ 95% by HPLC
  • Cell permeable N
  • Emission max.
  • Excitation max.
  • Peptide Sequence Ac-Leu-Glu-His-Asp-AFC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Protect from Moisture Protect from moisture
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.

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