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Merck - 219402-25UG - CATHEPSIN L HUMAN LIV 25 UG (Each)

  • MFR SKU: 219402-25UG
  • ITEM #: 4147824
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ITEM #: 4147824
Cathepsin L, Human Liver^ Liquid. In 150 mM NaCl, 20 mM NaOAc, 1 mM EDTA, pH 5.0. The most powerful of the lysosomal proteinases, having a higher specific activity than cathepsins B and H in the degradation of a variety of physiological protein substances. Specific activity: 1000 mU/mg protein.
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Merck - 219402-25UG - CATHEPSIN L HUMAN LIV 25 UG (Each)

  • Item #: 4147824
  • MFR SKU: 219402-25UG
  • Overview Native cathepsin L from human liver. The most potent of the lysosomal proteinases, having a higher activity than cathepsins B and H in the degradation of a variety of physiological protein substrates. Cathepsin L is believed to be responsible for the generation of endostatin from NC1 domain in collagen XVII.
  • Note: 1 mU = 1 milliunit.
  • Catalogue Number 219402
  • Brand Family Calbiochem®
  • References Kurata, M., et al. 2001. J. Biochem. (Tokyo) 130, 857.
  • Ferreras, M., et al. 2000. FEBS Lett. 486, 247.
  • Baricos, W.H., et al. 1988. Biochem. J. 252, 301.
  • Mc. Donald, J.K., et al. 1988. Biochem. Biophys. Res. Commun. 151, 827.
  • Unit of Definition One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol of Z-FR-AFC per min at 25° C, pH 5.5.
  • EC number 3.4.22.15
  • Form Liquid
  • Formulation In 400 mM Na. Cl, 20 mM malonate buffer, 1 mM EDTA, pH 5.5.
  • Quality Level MQ100
  • Source Prepared from tissue of individuals that have been shown by certified tests to be negative for HBs. Ag and for antibodies to HIV and HCV.
  • Concentration Label Please refer to vial label for lot-specific concentration
  • Ship Code Dry Ice Only
  • Toxicity Standard Handling
  • Storage ≤ -70° C
  • Avoid freeze/thaw Avoid freeze/thaw
  • Do not freeze Ok to freeze
  • Special Instructions Following initial thaw, aliquot and freeze (-70° C).

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