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Merck - 219555-1MG - Cathepsin K Substrate II, Fluorogenic | Calbiochem | 1MG

  • MFR SKU: 219555-1MG
  • ITEM #: 11592073
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ITEM #: 11592073
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK ( k cat /Km = 0.426 µM¹ S¹), but not by Cathepsins B/L/S/F/H/V.
This listing is for 1 mg Plastic ampoule

Merck - 219555-1MG - Cathepsin K Substrate II, Fluorogenic | Calbiochem | 1MG

  • Item #: 11592073
  • MFR SKU: 219555-1MG
  • Overview An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK ( k cat /K m = 0.426 µ M -1 S -1 ), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK -/- mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates.
  • Catalogue Number 219555
  • Brand Family Calbiochem®
  • Synonyms Abz-HPG~GPQ-EDNph
  • References Lecaille, F., et al. 2003. Biochem. J. 375, 307.
  • Form Bright yellow solid
  • Formulation Supplied as a trifluoroacetate salt.
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Hygroscopic Hygroscopic
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 95% by HPLC
  • Emission max.
  • Excitation max.
  • Peptide Sequence Abz-His-Pro-Gly~Gly-Pro-Gln-EDDnp
  • Ship Code Blue Ice Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Protect from Moisture Protect from moisture
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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