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Merck - 219557-5MG - Cerulenin, Cephalosporium caerulens - CAS 17397-89-6 - Calbiochem

  • MFR SKU: 219557-5MG
  • ITEM #: 3441788
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ITEM #: 3441788
Cerulenin, Cephalosporium caerulens^ White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. An antifungal antibiotic that inhibits sterol and fatty acid biosynthesis. In fatty acid synthesis, reported to bind in equimolar ratio to beta-keto-acyl-ACP synthase. 5mg.
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Merck - 219557-5MG - Cerulenin, <i>Cephalosporium caerulens</i> - CAS 17397-89-6 - Calbiochem

  • Item #: 3441788
  • MFR SKU: 219557-5MG
  • Overview An antifungal antibiotic that inhibits sterol and fatty acid biosynthesis. In fatty acid synthesis, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. Also shown to inhibit feeding and induce dramatic weight loss in mice.
  • Catalogue Number 219557
  • Brand Family Calbiochem®
  • References Loftus, T.M., et al. 2000. Science 288, 2379.
  • Inokashi, J., et al. 1994. Mol. Gen. Genet. 244, 90.
  • Schneider, F., et al. 1993. Biochim. Biophys. Acta 1152, 243.
  • CAS number 17397-89-6
  • Form White to off-white solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target sterol & fatty acid biosynthesis
  • Purity ≥ 98% by TLC
  • RTECS JR1670000
  • R Phrase R: 20/21/22
  • Harmful by inhalation, in contact with skin and if swallowed.
  • S Phrase S: 36
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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