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Merck - 236011-5MG - COX-2 Inhibitor I | CAS 416901-58-1 | Calbiochem | 5 MG

  • MFR SKU: 236011-5MG
  • ITEM #: 6281206
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ITEM #: 6281206
The COX-2 Inhibitor I, also referenced under CAS 416901-58-1, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.
This listing is for 5 mg Plastic ampoule

Merck - 236011-5MG - COX-2 Inhibitor I | CAS 416901-58-1 | Calbiochem | 5 MG

  • Item #: 6281206
  • MFR SKU: 236011-5MG
  • Overview A cell-permeable potent and selective inhibitor of COX-2 from human monocytes (IC 50 = 650 nM) and in whole blood (IC 50 = 4.3 µ M). Displays only very weak activity against COX-1 from human platelets (IC 50 > 10 µ M) and in whole blood (IC 50 > 100 µ M).
  • Catalogue Number 236011
  • Brand Family Calbiochem®
  • Synonyms LM-1685, Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate
  • References Palomer, A., et al. 2002. J. Med. Chem. 45, 1402.
  • CAS number 416901-58-1
  • ATP Competitive N
  • Form White solid
  • Hill Formula CHClNOS
  • Chemical formula CHClNOS
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target COX-2 from human monocytes 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 650 nM against COX-2 from human monocytes; 4.3 µ M against COX-2 in whole blood
  • Purity ≥ 97% by HPLC
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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