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Merck - 23-027 - 23-027, b-catenin Protein, activated, 10 µg Activated, full length, recombinant human beta-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a (Item # 14-492). For use in Enzyme Assays. Behaves as a

  • MFR SKU: 23-027
  • ITEM #: 11574838
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ITEM #: 11574838
beta-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion comple x , regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that governs cell fate in early embryogenesis. The regulation of beta-catenin turnover in the cells is governed by its phosphorylation status which allows the targeting of ubiquitin-dependent proteolysis. Altered levels of protein e x pression as well as genetic mutations of beta-catenin...
ITEM #: 11574838
beta-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion comple x , regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that governs cell fate in early embryogenesis. The regulation of beta-catenin turnover in the cells is governed by its phosphorylation status which allows the targeting of ubiquitin-dependent proteolysis. Altered levels of protein e x pression as well as genetic mutations of beta-catenin have been implicated in a number of human cancers.
Synonyms: Catenin beta-1
Application: Ubiquitination Cascade Comoponent: Substrate
: UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
23-027, b-catenin Protein, activated, 10 µg Activated, full length, recombinant human beta-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a (Item # 14-492). For use in Enzyme Assays. Behaves as a substrate in ubiquitin ass
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Merck - 23-027 - 23-027, b-catenin Protein, activated, 10 µg Activated, full length, recombinant human beta-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a (Item # 14-492). For use in Enzyme Assays. Behaves as a

  • Item #: 11574838
  • MFR SKU: 23-027
Technical Specs
  • Catalogue Number 23-027
  • Brand Family Upstate
  • Trade Name
  • Upstate
  • b-catenin Protein, activated, 10 µg
  • Overview N-terminal GST-tagged, recombinant human Smurf1 full length, expressed in E coli.
  • Alternate Names
  • Catenin beta-1
  • Background Information β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that governs cell fate in early embryogenesis. The regulation of β-catenin turnover in the cells is governed by its phosphorylation status which allows the targeting of ubiquitin-dependent proteolysis. Altered levels of protein expression as well as genetic mutations of β-catenin have been implicated in a number of human cancers.
  • Quality Level MQ100
  • Application Activated, full length, recombinant human β-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a (Item # 14-492). For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.
  • Key Applications
  • Enzyme Assays
  • Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
  • Cascade Component Substrate
  • Entrez Gene Number
  • NM_001904
  • Purification Method Purified using immobilized metal affinity chromatography.
  • Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
  • Material Size 10 µg
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