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Merck - 23-027M - b-catenin Protein, activated, 250 µg

  • MFR SKU: 23-027M
  • ITEM #: 11574839
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ITEM #: 11574839
Activated, full length, recombinant human β-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.

Merck - 23-027M - b-catenin Protein, activated, 250 µg

  • Item #: 11574839
  • MFR SKU: 23-027M
  • Catalogue Number 23-027M
  • Brand Family Upstate
  • Trade Name
  • Upstate
  • b-catenin Protein, activated, 250 µg
  • Overview AXIS Axon Isolation Devices - culture dish mounted, 150 µm long channels, 5 devices
  • Alternate Names
  • Catenin beta-1
  • Background Information β-catenin is a multifunctional protein; it is a central component of the cadherin cell adhesion complex, regulating the control of cell adhesion and plays an essential role in the Wingless/Wnt signaling pathway that governs cell fate in early embryogenesis. The regulation of β-catenin turnover in the cells is governed by its phosphorylation status which allows the targeting of ubiquitin-dependent proteolysis. Altered levels of protein expression as well as genetic mutations of β-catenin have been implicated in a number of human cancers.
  • Quality Level MQ300
  • Application Activated, full length, recombinant human β-catenin. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using GSK-3a. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.
  • Key Applications
  • Enzyme Assays
  • Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
  • Cascade Component Substrate
  • Entrez Gene Number
  • NM_001904
  • Purification Method Purified using immobilized metal affinity chromatography.
  • Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
  • Material Size 250 µg

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