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Merck - 23-039 - Smad7

  • MFR SKU: 23-039
  • ITEM #: 11574855
  • 0 Reviews / 0 Questions
$980.00
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ITEM #: 11574855
Catalogue Number 23-039
Brand Family Upstate
Trade Name
  • Upstate

Smad7
Alternate Names
  • Mothers against decapentaplegic homologue 7
  • MAD homologue 7
  • Mothers against DPP homologue 7
  • Mothers against decapentaplegic homologue 8
  • MADH7
  • MADH8

Background Information The TGF-β signalling cascade regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, adhesion...
ITEM #: 11574855
Catalogue Number 23-039
Brand Family Upstate
Trade Name
  • Upstate

Smad7
Alternate Names
  • Mothers against decapentaplegic homologue 7
  • MAD homologue 7
  • Mothers against DPP homologue 7
  • Mothers against decapentaplegic homologue 8
  • MADH7
  • MADH8

Background Information The TGF-β signalling cascade regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, adhesion and migration. It plays a fundamental role in a number of different physiological and pathological processes, such as embryonic development, adult homoeostasis, tumourigenesis and tissue fibrogenesis. Smad7 has been identified as a key negative regulator of TGF-β signalling, antagonising it through multiple mechanisms in both the cytoplasm and in the nucleus. Altered expression of Smad7 is often associated with human diseases, such as cancer, tissue fibrosis and inflammatory diseases.
Quality Level MQ100
Key Applications
  • Enzyme Assays

Cascade Component Substrate
Entrez Gene Number
  • NM_005904

Purification Method Purified using immobilized metal affinity chromatography.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Material Size 10 µg
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Merck - 23-039 - Smad7

  • Item #: 11574855
  • MFR SKU: 23-039

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