Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - 23-043M - Kit Protein, 250 µg

  • MFR SKU: 23-043M
  • ITEM #: 11574862
  • 0 Reviews / 0 Questions
$5,598.50
  • Saw It For Less?
Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 11574862
Recombinant human Kit, amino acids 544-end. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

Merck - 23-043M - Kit Protein, 250 µg

  • Item #: 11574862
  • MFR SKU: 23-043M
  • Catalogue Number 23-043M
  • Brand Family Upstate
  • Trade Name
  • Upstate
  • Kit Protein, 250 µg
  • Alternate Names
  • Mast/stem cell growth factor receptor
  • Proto-oncogene c-Kit
  • Tyrosine-protein kinase Kit
  • CD_antigen=CD117
  • Background Information Kit belongs to the family of type III receptor tyrosine kinases. It mediates the cellular response to stem cell factor and plays a major role in survival, expansion and differentiation of haematopoietic progenitor cells and reproductive stem cells. The activation of Kit is tightly regulated and uncontrolled Kit activity contributes to the growth of diverse human tumours. Gain-of-function mutations have been described in a number of malignancies, including acute myeloid leukaemia, small cell lung cancer, gastrointestinal stromal tumours and testicular cancer. Negative regulation of Kit signalling has been shown to occur mainly through ubiquitin-mediated internalization and degradation of the receptor.
  • Quality Level MQ300
  • Application Recombinant human Kit, amino acids 544-end. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
  • Key Applications
  • Enzyme Assays
  • Specific Activity For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
  • Cascade Component Substrate
  • Entrez Gene Number
  • X06182
  • Purification Method Purified using glutathione sepharose.
  • Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
  • Material Size 250 µg

There are no questions about this product yet. Be the first to ask a question.

0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Recently Viewed Items