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Merck - 23-055 - Cardiac Troponin I, 10 µg

  • MFR SKU: 23-055
  • ITEM #: 11574887
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$957.50
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ITEM #: 11574887
Full length, recombinant human Cardiac Troponin I. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

Merck - 23-055 - Cardiac Troponin I, 10 µg

  • Item #: 11574887
  • MFR SKU: 23-055
  • Catalogue Number 23-055
  • Brand Family Upstate
  • Trade Name
  • Upstate
  • Cardiac Troponin I, 10 µg
  • Alternate Names
  • Troponin I
  • cardiac muscle
  • TNNI3
  • TNNC1
  • Background Information Troponin is a complex of three regulatory proteins (Troponin I, Troponin T and Troponin C). It is located on the actin filament and is essential for the calcium-mediated regulation of skeletal and cardiac muscle contraction. There are tissue-specific isoforms of Troponin I, T and C and two subtypes (Cardiac Troponin I and T) are released when the heart muscle has been damaged, such as during a heart attack. The more damage there is to the heart, the greater the amount of Troponin I and T there will be in the blood and currently, Cardiac Troponin I and T are used as the preferred biochemical markers for the diagnosis of myocardial infarction. It has also been demonstrated that Cardiac Troponin I is targeted for degradation by MuRF1, an E3 ubiquitin ligase that has been linked to muscle atrophy
  • Quality Level MQ100
  • Application Full length, recombinant human Cardiac Troponin I. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
  • Key Applications
  • Enzyme Assays
  • Cascade Component Substrate
  • Entrez Gene Number
  • NM_000363
  • Purification Method Purified using immobilized metal affinity chromatography.
  • Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
  • Material Size 10 µg

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