Image is an illustration, may not reflect the exact product sold.


Other products by Merck

Merck - 23-059M - TRAF6, active

  • MFR SKU: 23-059M
  • ITEM #: 11574897
    • 0 out of 5 stars
    • 5 Star
      0 %
    • 4 Star
      0 %
    • 3 Star
      0 %
    • 2 Star
      0 %
    • 1 Star
      0 %
  • 0 Reviews / 0 Questions
$5,598.50
  • Saw It For Less?

  • Please complete this captcha to continue

Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 11574897
Catalogue Number 23-059M
Brand Family Upstate
Trade Name
  • Upstate

TRAF6, active
Alternate Names
  • TNF receptor-associated factor 6
  • Interleukin-1 signal transducer
  • RING finger protein 85

Background Information TRAF6 is a ubiquitin ligase essential for the activation of NF-κB and MAP kinases in multiple signalling pathways including those emanating from the tumour-necrosis-factor receptor (TNFR) and interleukin-1/Toll-like...
ITEM #: 11574897
Catalogue Number 23-059M
Brand Family Upstate
Trade Name
  • Upstate

TRAF6, active
Alternate Names
  • TNF receptor-associated factor 6
  • Interleukin-1 signal transducer
  • RING finger protein 85

Background Information TRAF6 is a ubiquitin ligase essential for the activation of NF-κB and MAP kinases in multiple signalling pathways including those emanating from the tumour-necrosis-factor receptor (TNFR) and interleukin-1/Toll-like receptors (IL-1R/TLR). TRAF6 also transduces signals from receptors such as CD40 and RANK and may be essential for the formation of functional osteoclasts. Studies indicate that amplification of the TRAF6 locus is a somatic and frequent event in several human cancer types and is a commonly amplified oncogene bridging RAS and NF-κB in lung cancer. Inhibition of TRAF6 in lung cancer cells has been shown to suppress NF-κB activation, anchorage-independent growth and tumour formation.
Quality Level MQ100
Key Applications
  • Enzyme Assays

Cascade Component E3
Entrez Gene Number
  • BC031052

Purification Method Purified using glutathione sepharose.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Material Size 250 µg
Read More >>

Merck - 23-059M - TRAF6, active

  • Item #: 11574897
  • MFR SKU: 23-059M
Questions & Answers

There are no questions about this product yet. Be the first to ask a question.

Add Question
0 Customer Ratings & Reviews
0 out of 5 stars
5 Star
0 %
4 Star
0 %
3 Star
0 %
2 Star
0 %
1 Star
0 %

Review this product

Tell us about your personal experience

Write a review

Recently Viewed Items