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Merck - 251400-5MG - D609, Potassium Salt | CAS 83373-60-8 | Calbiochem | 5MG

  • MFR SKU: 251400-5MG
  • ITEM #: 3441800
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ITEM #: 3441800
D609, Potassium^ (Tricyclodecan-9-yl-xanthogenate, potassium). Off-white solid. Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (Ki = 5 - 10 mM). Does not inhibit phosphatidylinositol-specific phospholipase C, phospholipase A or phospholipase D. Purity: >= 97% by TLC.
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Merck - 251400-5MG - D609, Potassium Salt | CAS 83373-60-8 | Calbiochem | 5MG

  • Item #: 3441800
  • MFR SKU: 251400-5MG
  • Overview Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (K i = 5-10 µ M). Does not inhibit phosphatidylinositol-specific phospholipase C, phospholipase A, or phospholipase D. Also reported to inhibit LPS-stimulated ERK activation via its inhibitory effect on PLC. Inhibits angiogenesis by preventing the synthesis of basement membrane.
  • Catalogue Number 251400
  • Brand Family Calbiochem®
  • Synonyms Tricyclodecan-9-yl-xanthogenate, K
  • References Monick, M.M., et al. 1999. J. Immunol. 162, 3005.
  • Lozanski, G., et al. 1997. Biochem. J. 328, 271.
  • Maragoudakis, M.E., et al. 1993. Kidney Int. 43, 147.
  • Doppler, C., et al. 1992. AIDS Res. Human Retroviruses 8, 245.
  • Schutze, S., et al. 1992. Cell 71, 765.
  • Sauer, G., et al. 1990. Cancer Lett. 53, 97.
  • Muller-Decker, K. 1989. Biochem. Biophys. Res. Commun. 162, 198.
  • Amtmann, E., et al. 1987. Biochem. Pharmacol. 36, 1545.
  • Sauer, G., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 3263.
  • CAS number 83373-60-8
  • ATP Competitive N
  • Form Off-white powder
  • Hill Formula CHOS · K
  • Chemical formula CHOS · K
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target pc-specificphopholipase c i $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target K i " value=" Biological Information"
  • br> Primary Target K<sub>i</sub> 5-10 µ M against phosphatidylcholine (PC)-specific phospholipase C
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Material is very labile once in solution (1.5 day half-life in tissue culture medium).

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