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Merck - 252750-1GM - Deferoxamine Mesylate | CAS 138-14-7 | Calbiochem | 1GM

  • MFR SKU: 252750-1GM
  • ITEM #: 3441802
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ITEM #: 3441802
Deferoxamine Mesylate^ HYGROSCOPIC. Parenteral iron chelating agent. Commonly used in therapy as a chelator of ferric iron in disorders of iron overload. Completely protects against dopamine-induced cell death. Purity: >=95% by TLC. Soluble in 5% water. FW: 656.8. Off-white solid, 1g.
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Merck - 252750-1GM - Deferoxamine Mesylate | CAS 138-14-7 | Calbiochem | 1GM

  • Item #: 3441802
  • MFR SKU: 252750-1GM
  • Overview Parenteral iron chelating agent. Commonly used in therapy as a chelator of ferric iron in disorders of iron overload. Completely protects against dopamine-induced cell death. Has also been shown to interfere with hydroxyl radical formation, which mediates tissue damage in several disease states. Shows anti-proliferative effect on vascular smooth muscle cells in vitro and in vivo . Can also inhibit the oxidative chemistry of peroxynitrite by reaction of the hydroxamic acid moieties with trans -peroxynitrous acid.
  • Catalogue Number 252750
  • Brand Family Calbiochem®
  • Synonyms Desferrioxamine Mesylate, DFOM, Iron Chelator II
  • References Bergeron, R.J., et al. 1996. J. Med. Chem. 39, 1575.
  • Ben-Shachar, D., et al. 1995. J. Neurochem. 64, 718.
  • Denicola, A., et al. 1995. Free Radic. Biol. Med. 19, 11.
  • Dzwigaj, S., and pererat, H., 1995. Free Radic. Res. 14, 103.
  • Dang, S., et al. 1994. Res. Commun. Mol. Pathol. Pharmacol. 86, 43.
  • Porreca, E., et al. 1994. Arterioscler. Thromb. 14, 299.
  • CAS number 138-14-7
  • Form Faint yellow powder
  • Hill Formula CHNO· CHOS
  • Chemical formula CHNO· CHOS
  • Hygroscopic Hygroscopic
  • Structure formula Image
  • Quality Level MQ100
  • Purity 92.5-100% by TLC
  • RTECS UG5310000
  • R Phrase R: 22-36/37/38-40-42/43
  • Harmful if swallowed.
  • Irritating to eyes, respiratory system and skin.
  • Limited evidence of a carcinogenic effect.
  • May cause sensitization by inhalation and skin contact.
  • S Phrase S: 22-26-36
  • Do not breathe dust.
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful & Carcinogenic / Teratogenic
  • Storage +2° C to +8° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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