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Merck - 266785-5MG - Diacylglycerol Kinase Inhibitor I (DAG ) | CAS 93076-89-2 | Calbiochem | 5MG

  • MFR SKU: 266785-5MG
  • ITEM #: 5015668
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ITEM #: 5015668
Diacylglycerol Kinase Inhibitor I^ ( {R59022; 6-{2-{4-[(p-fluorophenyl)phenylmethylene]-1-piperidinyl}ethyl}-7-methyl-5H-thiazolo(3, 2-a)pyrimidine-5-one}). White to off-white solid. Potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism.
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Merck - 266785-5MG - Diacylglycerol Kinase Inhibitor I (DAG ) | CAS 93076-89-2 | Calbiochem | 5MG

  • Item #: 5015668
  • MFR SKU: 266785-5MG
  • Overview Potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism. Inhibits diacylglycerol kinase (IC 50 = 2.8 µ M) without affecting phosphodiesterase or phosphatidylinositol kinase. Weak dopamine D 2 and histamine H 1 antagonist and strong serotonin S 2 antagonist.
  • Catalogue Number 266785
  • Brand Family Calbiochem®
  • Synonyms R59022, 6-{2-{4-[( p -Fluorophenyl)phenylmethylene]-1-piperidinyl}ethyl}-7-methyl-5H-thiazolo(3, 2-a)pyrimidine-5-one
  • References Goin, M., et al. 1993. FEBS Lett. 316, 68.
  • Ohtsuka, T., et al. 1990. J. Biol. Chem. 265, 15418.
  • de Chaffoy de Courcelles, D., et al. 1985. J. Biol. Chem. 260, 15762.
  • CAS number 93076-89-2
  • ATP Competitive N
  • Form White solid
  • Hill Formula CHFNOS
  • Chemical formula CHFNOS
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Diacylglycerol Kinase
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage +15° C to +30° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, store in the refrigerator (4° C). Stock solutions are stable for up to 3 months at 4° C.

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