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Merck - 309795-250MG - DIDS, Disodium Salt | CAS 53005-05-3 | Calbiochem | 250MG

  • MFR SKU: 309795-250MG
  • ITEM #: 3441314
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ITEM #: 3441314
DIDS, Disodium^ (4, 4'' -Diisothiocyanostilbene-2, 2'' -disulfonic acid, sodium). Yellow solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Binds covalently and irreversibly to the outer surface of human erythrocyte membrane. Inhibits ATP transport into endoplasmic reticulum vesicles.
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Merck - 309795-250MG - DIDS, Disodium Salt | CAS 53005-05-3 | Calbiochem | 250MG

  • Item #: 3441314
  • MFR SKU: 309795-250MG
  • Overview Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl – uptake (IC 50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
  • Catalogue Number 309795
  • Brand Family Calbiochem®
  • Synonyms 4, 4-Diisothiocyanostilbene-2, 2-disulfonic Acid, 2Na
  • References Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
  • Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
  • Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
  • Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.
  • CAS number 53005-05-3
  • ATP Competitive N
  • Form Yellow solid
  • Hill Formula CHNOS · 2Na
  • Chemical formula CHNOS · 2Na
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Cl- uptake 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 150 nM inhibiting Cl- uptake in neuroblastoma cells
  • Purity ≥ 85% by TLC
  • Cell permeable N
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage -20° C
  • Protect from Light Protect from light
  • Protect from Moisture Protect from moisture
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 2 months at -20° C.

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