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Merck - 309866-100MG - Diltiazem, Hydrochloride | CAS 33286-22-5 | Calbiochem | 100MG

  • MFR SKU: 309866-100MG
  • ITEM #: 6280616
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ITEM #: 6280616
Diltiazem, HCl^ White solid. Synthetic benzothiazepine that acts as an L-type Ca2+ channel antagonist. Similar in function to Nifedipine (Cat. No. 481981) and Verapamil (Cat. No. 676777). Has negative inotropic effects on the heart.
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Merck - 309866-100MG - Diltiazem, Hydrochloride | CAS 33286-22-5 | Calbiochem | 100MG

  • Item #: 6280616
  • MFR SKU: 309866-100MG
  • Overview Synthetic benzothiazepine that acts as an L-type Ca 2+ channel antagonist. Similar in function to Nifedipine (Cat. No. 481981 ) and Verapamil (Cat. No. 676777 ). Has negative inotropic effects on the heart. Strongly suppresses conductance at the A-V node and automaticity at the S-A node. Has also been shown to regulate Ca 2+ release from intracellular stores in neutrophils.
  • Catalogue Number 309866
  • Brand Family Calbiochem®
  • Synonyms L-Type Calcium Channel Blocker II
  • References van Zwieten, P.A., and Pfaffendorf, M. 1993. J. Hypertens. Suppl. 11, S3.
  • Rosales, C., and Brown, E.J. 1992. J. Biol. Chem. 267, 1443.
  • Julian, D.G. 1987. Am. J. Cardiol. 59, 37J.
  • Campbell, K.P., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 2792.
  • Gallizzi, J.P., et al. 1986. J. Biol. Chem. 261, 1393.
  • Garcia, M.L., et al. 1986. J. Biol. Chem. 261, 8146.
  • CAS number 33286-22-5
  • ATP Competitive N
  • Form White solid
  • Hill Formula CHNOS · HCl
  • Chemical formula CHNOS · HCl
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target L-type Ca2+ channel
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • RTECS DL0310000
  • R Phrase R: 22-40
  • Harmful if swallowed.
  • Limited evidence of a carcinogenic effect.
  • S Phrase S: 36
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Harmful & Carcinogenic / Teratogenic
  • Storage +15° C to +30° C
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, store in the refrigerator (4° C). Stock solutions are stable for up to 2 weeks at 4° C.

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