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Merck - 322133-100MG - DSP WATER-SOLUBLE 100MG (Each)

  • MFR SKU: 322133-100MG
  • ITEM #: 6310779
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ITEM #: 6310779
DSP Water-Soluble 100Mg^ 3, 3-Dithio-bis-(sulfosuccinimidyl)propionate, DTSSP, Sulfo-DSP Form Off-white to light tan solid.Storage +2C to +8C.Purity =94% by HPLC.Bifunctional cross-linker. The disulfide bond can be cleaved with 1% NaBH4, 50 mM DTT, or 100 mM Beta -mercaptoethanol.
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Merck - 322133-100MG - DSP WATER-SOLUBLE 100MG (Each)

  • Item #: 6310779
  • MFR SKU: 322133-100MG
  • Overview Bifunctional cross-linker. The disulfide bond can be cleaved with 1% NaBH 4 , 50 mM DTT, or 100 mM β-mercaptoethanol. Has been used to immobilize proteins on supports containing amino groups.
  • Catalogue Number 322133
  • Brand Family Calbiochem®
  • Synonyms 3, 3-Dithio- bis -(sulfosuccinimidyl)propionate, DTSSP, Sulfo-DSP
  • References Howard, A.D., et al. 1985. J. Biol. Chem. 260, 10833.
  • Lee, W.T., and Conrad, D.H. 1985. J. Immunol. 134, 518.
  • D'Souza, S.E., et al. 1988. J. Biol. Chem. 263, 3943.
  • Yamada, H., et al. 1981. Biochem. 20, 4836.
  • Annunziato, M.E., et al. 1993. Bioconjugate Chem. 4, 212.
  • Form Off-white to light tan solid
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 94% by HPLC
  • R Phrase R: 36/37/38
  • Irritating to eyes, respiratory system and skin.
  • S Phrase S: 26-36
  • In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
  • Wear suitable protective clothing.
  • Ship Code Ambient Temperature Only
  • Toxicity Irritant
  • Storage +2° C to +8° C
  • Protect from Moisture Protect from moisture
  • Do not freeze Ok to freeze
  • Special Instructions Following each use, purge the original vial with inert gas and refrigerate (4° C). Unstable in aqueous solution; reconstitute just prior to use. Alternatively, the solid DSP can be added directly to the sample to minimize hydrolysis. Hydrolysis is more pronounced in dilute protein solutions and can, therefore, be minimized by using more concentrated protein solutions (>5 mg/ml). For storage of stock solutions, reconstitute in anhydrous DMSO.

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