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Merck - 324483-5MG - Ebselen | CAS 60940-34-3 | Calbiochem | 5MG

  • MFR SKU: 324483-5MG
  • ITEM #: 3441318
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ITEM #: 3441318
Ebselen^ [2-Phenyl-1, 2-benzisoselenazol-3(2H)-one; PZ51]. Non-selective inhibitor of the cyclooxygenase activity of prostaglandin H synthase 1 and 2. An excellent scavenger of peroxynitrite. Purity: >=98% by TLC. Soluble in DMSO and ethanol. CAS: 60940-34-3. FW: 274.2. Crystalline solid, 5mg.
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Merck - 324483-5MG - Ebselen | CAS 60940-34-3 | Calbiochem | 5MG

  • Item #: 3441318
  • MFR SKU: 324483-5MG
  • Overview A cell-permeable, non-selective inhibitor of COX-1 and COX-2. An excellent scavenger of peroxynitrite. Glutathione peroxidase mimetic. Inhibits radiation-induced apoptosis in thymocytes by scavenging peroxides. A neuroprotective agent active against acute focal ischemic injury. Inhibits LPS-induced NF-κ B nuclear translocation and LPS-induced phosphorylation of JNK.
  • Catalogue Number 324483
  • Brand Family Calbiochem®
  • Synonyms 2-Phenyl-1, 2-benzisoselenazol-3(2H)-one, PZ51
  • References Shimohashi, N., et al. 2000. J. Cell Biochem . 78, 595.
  • Ramakrishnan, N., et al. 1996. Biochem. Pharmacol. 51, 1443.
  • Ullrich, V., et al. 1996. Biochem. Pharmacol. 52, 15.
  • Dawson, D.A., et al. 1995. Neurosci. Lett. 185, 65.
  • Wang, J.F., et al. 1992. Hepatology 5, 112.
  • Maiorino, M., et al. 1988. Biochem. Pharmacol. 37, 2267.
  • Parnham, M.J., and Graf, E. 1987. Biochem. Pharmacol. 36, 3095.
  • Parnham, M.J., and Kindt, S. 1984. Biochem. Pharmacol. 33, 3247.
  • CAS number 60940-34-3
  • ATP Competitive N
  • Form Lyophilized solid
  • Hill Formula CHNOSe
  • Chemical formula CHNOSe
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target COX-1, COX-2
  • Purity ≥ 98% by TLC
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstituion, aliquot and freeze (-20° C). Stock solutions are stable for up to 3 months at -20° C.

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