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Merck - 341249-5MG - FAAH Inhibitor II | CAS 546141-08-6 | Calbiochem | 5MG

  • MFR SKU: 341249-5MG
  • ITEM #: 6281415
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ITEM #: 6281415
The FAAH Inhibitor II, also referenced under CAS 546141-08-6, controls the biological activity of FAAH. This small molecule/inhibitor is primarily used for Cell Signaling applications.
This listing is for 5 mg Alu drum

Merck - 341249-5MG - FAAH Inhibitor II | CAS 546141-08-6 | Calbiochem | 5MG

  • Item #: 6281415
  • MFR SKU: 341249-5MG
  • Overview A cell-permeable carbamate compound that acts as a potent, selective, and irreversible inhibitor of fatty acid amide hydrolase (FAAH; IC 50 = 4.6 nM in brain membranes). Shown to block anandamide (Cat. No. 172100 ) breakdown in rat cortical neurons (IC 50 = 500 pM) and modulate anxiety in rats (ID 50 = 0.15 mg/Kg). Does not affect the activities of several serine hydrolases (IC 50 > 30 µ M), including AChE (acetylcholinesterase), BCh (butyrylcholinesterase) and MGL (monoglyceride lipase). It also does not interfere with the binding of anandamide to cannabinoid receptors CB1 and CB2 (IC 50 > 100 µ M), as well as several ion-channels and neurotransmitter transporters.
  • Catalogue Number 341249
  • Brand Family Calbiochem®
  • Synonyms URB597, Cyclohexylcarbamic acid-3-carbamoyl-biphenyl-3-yl Ester, 3-Carbamoyl-biphenyl-3-yl-cyclohexylcarbamate
  • References Kathuria, S., et al. 2003. Nat. Med. 9, 76.
  • CAS number 546141-08-6
  • ATP Competitive N
  • Form White crystalline solid
  • Hill Formula CHNO
  • Chemical formula CHNO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target FAAH 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 4.6 nM against FAAH
  • Purity ≥ 98% by NMR
  • Cell permeable Y
  • Ship Code Ambient Temperature Only
  • Toxicity Toxic
  • Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution aliquot, purge with an inert gas, and freeze (-20° C). Stock solutions are stable for up to 1 month at -20° C.
  • Packaged under inert gas Packaged under inert gas

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