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Merck - 341501-10MG - FeTMPyP | Calbiochem | 10MG

  • MFR SKU: 341501-10MG
  • ITEM #: 3441331
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ITEM #: 3441331
FeTMPyP^ [5, 10, 15, 20-Tetrakis(N-methyl-4'-pyridyl)porphinato iron (III) chloride; FeIIITMPYP(Cl)]. Catalyzes the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-). Prevents oxidation of lipid components by peroxynitrite. Purity: >=95% by TLC. Soluble in water. FW: 909.9. Black solid, 10mg.
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Merck - 341501-10MG - FeTMPyP | Calbiochem | 10MG

  • Item #: 3441331
  • MFR SKU: 341501-10MG
Technical Specs
  • Overview Catalyzes the isomerization of peroxynitrite (ONOO – ) to nitrate (NO 3 – ) under physiological conditions and at realistic dose-derived concentrations (K cat = 2.2 x 10 6 M -1 s -1 ). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O 2 · ). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH · ) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS).
  • Catalogue Number 341501
  • Brand Family Calbiochem®
  • Synonyms 5, 10, 15, 20-Tetrakis(N-methyl-4-pyridyl)porphinato Iron (III) Chloride, Fe III TMPyP(Cl)
  • References Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
  • Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
  • Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
  • Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
  • Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 46, 703.
  • ATP Competitive N
  • Form Brown solid
  • Hill Formula CHClFeN
  • Chemical formula CHClFeN
  • Hygroscopic Hygroscopic
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target Peroxynitrite (ONOO-) 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions
  • Purity ≥ 90% by TLC
  • Cell permeable N
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage -20° C
  • Protect from Light Protect from light
  • Hygroscopic Hygroscopic
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 4 months at -20° C.
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