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Merck - 344079-100MG - Flurbiprofen - CAS 5104-49-4 - Calbiochem

Name: Merck - 344079-100MG - Flurbiprofen - CAS 5104-49-4 - Calbiochem
SKU: 344079-100MG
Price: 115.95 USD
Availability: InStock

$115.95

Stock Status: SHIPS SOON (reserve your unit today)
Average lead time for this brand: 2-3 weeks. Specific products may vary.

ITEM #: 6280833
A mixture of S(+) and R(-) enantiomers.
This listing is for 100 mg Alu drum

Overview A mixture of S(+) and R(–) enantiomers. A cell-permeable, non-steroidal anti-inflammatory agent that acts as a potent inhibitor of cyclooxygenase (IC 50 = 5 nM for LPS-induced COX in human peripheral blood cells). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Suppresses iNOS expression in RAW 264.7 macrophages. Reduces microglial activation and β-amyloid deposit in APP+PS1 transgenic mice.
Catalogue Number 344079
Brand Family Calbiochem®
Synonyms (±)-2-Fluoro-α-methyl[1, 1-biphenyl]-4-acetic Acid, U-27182
References Jantzen, P.T., et al. 2002. J. Neurosci. 22, 2246.
Hinz, R., et al. 2001. Pharmacol. Res. 18, 151.
Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312.
Range, S.P., et al. 2000. Eur. Respir. J. 15, 751.
van Haeringen, N.J., et al. 2000. J. Ocul. Pharmacol. Ther. 16, 353.
Curnock, A.P., et al. 1997. J. Pharmacol. Exp. Ther. 282, 339.
Reindeau, D., et al. 1997. Can. J. Physiol. Pharmacol. 75, 1088.
Wechter, W.J., et al. 1997. Cancer Res. 57, 4316.
Karmali, R.A., and Marsh, J. 1986. Prostaglandins Leukot. Med. 23, 11.
Karmali, R.A., and Marsh, J. 1985. Prostaglandins Leukot. Med. 20, 283.
CAS number 5104-49-4
ATP Competitive N
Form White solid
Hill Formula CHFO
Chemical formula CHFO
Reversible N

Structure formula Image
Quality Level MQ100
Primary Target Cyclooxygenase 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"

br> Primary Target IC<sub> 50</sub> 5 nM for LPS-induced COX
Purity ≥ 98% by HPLC
Cell permeable Y
RTECS DU8341000
R Phrase R: 25
Toxic if swallowed.
S Phrase S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Ship Code Ambient Temperature Only
Toxicity Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15° C to +30° C
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze at -20° C. Stock solutions are stable for up to 6 months at 4° C. Further dilution of stock solution in aqueous medium should be made just prior to use.

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