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Merck - 344095-25MG - Fluvastatin, Sodium Salt | CAS 93957-55-2 | Calbiochem | 25MG

  • MFR SKU: 344095-25MG
  • ITEM #: 3450364
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ITEM #: 3450364
Fluvastatin^ 25mg. (+/-)-(3R', 5S', 6E)-7-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]-3, 5-dihydroxy-6-heptenoate. Light yellow solid. Synthetic HMG-CoA reductase inhibitor that acts as anti-hypercholesterolemic agent. Purity:>=98% by HPLC. RTECS MJ9675050, CAS 93957-54-1. MW 411.5.
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Merck - 344095-25MG - Fluvastatin, Sodium Salt | CAS 93957-55-2 | Calbiochem | 25MG

  • Item #: 3450364
  • MFR SKU: 344095-25MG
  • Overview A synthetic HMG-CoA reductase inhibitor (IC 50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic agent. Decreases the basal MMP-1 levels in culture media of endothelial cells in a time- and dose-dependent manner. Inhibits the formation of TBA-reactive substances in Fe(II)-supported peroxidation of liposomes (IC 50 = 12 µ M). Also available as a 10 mM solution in H 2 O(Cat. No. 344096 ).
  • Catalogue Number 344095
  • Brand Family Calbiochem®
  • Synonyms (±)-(3R, 5S, 6E)-7-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]-3, 5-dihydroxy-6-heptenoate, sodium
  • References Yamamoto, A., et al. 2001. J. Pharm. Pharmacol. 53, 227.
  • Dansette, P.M., et al. 2000. Exp. Toxicol. Pathol. 52, 145.
  • Ikeda, U., et al. 2000. Hypertension 36 , 325.
  • Levy, R.I., et al. 1993. Circulation 87 (4 Suppl.), III45.
  • Tse, F.L.S. et al. 1992. J. Clin. Pharmacol. 32 , 630.
  • Yuan, J., et al. 1991. Atherosclerosis 87 , 147.
  • CAS number 93957-55-2
  • ATP Competitive N
  • Form Light yellow solid
  • Hill Formula CHFNNaO
  • Chemical formula CHFNNaO
  • Reversible N
  • Structure formula Image
  • Quality Level MQ100
  • Primary Target HMG-CoA reductase 50 $anchor_PDP_OverviewTab_Product_Biological_Info_Primary Target IC 50 " value=" Biological Information"
  • br> Primary Target IC<sub> 50</sub> 40-100 nM against HMG-CoA reductase in human liver microsomes
  • Purity ≥ 98% by HPLC
  • Cell permeable N
  • RTECS MJ9675050
  • R Phrase R: 62-63
  • Possible risk of impaired fertility.
  • Possible risk of harm to the unborn child.
  • S Phrase S: 22-24/25-36/37/39-45
  • Do not breathe dust.
  • Avoid contact with skin and eyes.
  • Wear suitable protective clothing, gloves and eye/face protection.
  • In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
  • Ship Code Ambient Temperature Only
  • Toxicity Carcinogenic / Teratogenic
  • Storage -20° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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