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Merck - 344300-5MG - sFRP-1 Inhibitor | CAS 915754-88-0 | Calbiochem | 5 MG

  • MFR SKU: 344300-5MG
  • ITEM #: 11575083
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ITEM #: 11575083
The sFRP-1 Inhibitor, also referenced under CAS 915754-88-0, controls the biological activity of sFRP-1. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
This listing is for 5 mg Glass bottle

Merck - 344300-5MG - sFRP-1 Inhibitor | CAS 915754-88-0 | Calbiochem | 5 MG

  • Item #: 11575083
  • MFR SKU: 344300-5MG
  • Overview A diphenylsulfone-sulfonamide compound that counteracts the antagonizing effect of SARP-2/sFRP-1 (secreted frizzled related protein-1) against Wnt-3/frizzled interaction and Wnt-3/frizzled-stimulated cellular functions (EC 50 = 1.27 µ M in a U2OS-based reporter assay) with a reported aqueous solubility of 26 µg/ml at pH 7.4 and in vitro half-lives of 12 and 26.7 min using rat and human microsomes, respectively.
  • Catalogue Number 344300
  • Brand Family Calbiochem®
  • Synonyms N-(3-(Dimethylamino)propyl)-2-ethyl-5-(phenylsulfonyl)benzenesulfonamide, Secreted Frizzled Related Protein-1 Inhibitor, Wnt Pathway Activator IV
  • References Gopalsamy, A., et al. 2008. J. Med. Chem. 51, 7670.
  • CAS number 915754-88-0
  • Form Clear oil
  • Hill Formula CHNOS
  • Chemical formula CHNOS
  • Structure formula Image
  • Quality Level MQ100
  • Purity ≥ 95% by HPLC
  • Ship Code Ambient Temperature Only
  • Toxicity Standard Handling
  • Storage +2° C to +8° C
  • Protect from Light Protect from light
  • Do not freeze Ok to freeze
  • Special Instructions Following reconstitution, aliquot and freeze (-20° C). Stock solutions are stable for up to 6 months at -20° C.
  • Packaged under inert gas Packaged under inert gas

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